Butyrate for Leaky Gut, Immunity, Hormones, Total Energy
Short chain fatty acids like butyrate, propionate, and acetate have some many important roles that it’s impossible to summarize. I’ll mention just butyrate but they all work together.
Here are some highlight starting with perhaps the most important first role in healing a leaky gut that overloads your body with toxins and drains and dysregulates the immune system.
When you seal up the leaky gut you can stop draining your whole body of energy and start to heal: detoxify, let the immune system to gain strength against pathogens, and get digestion working to extract energy from food. When the gut goes, everything goes.
Butyrate is the main source of fuel for colon cells so colonoyctes that are fed directly from the colon and not a blood supply.
When these are weak you get loose cell junctions or leaky gut.
What leaks through are toxins and endotoxins from pathogens like LPS, lipopolysaccharides.
You also get slow peristalsis or constipation.
Local inflammation and bloating follows as an attempt at healing a weak area.
Systemic inflammation can follow from a lack of butyrate in its larger hormonal type regulatory role in the immune system.
Some people find that histamines and mast cells respond to butyrate treatment. Jessica Kan (founder of BodyBio) says butyrate makes mast cell degranularize.
Butyrate also increases insulin sensitivity to burn carbs for energy rather that store as fat.
It also seems to have other roles in weight loss.
Butyrate is also important in Hormonal regulation
Increases testosterone.
Helps fertility, pcos, endometriosis, menstrual pain, etc.
Dr Stephen Gundry estimates we can get 10% of our energy from butyrate.
Butyrate experent Dr Chris Dammon says: “What is less appreciated is that butyrate, even at low levels, has direct effects on immune cells and neurons in the gut, body and brain,.”
“Butyrate could be the vitamin D of the next decade: the sunshine from within molecule.” Damman said. “Only 5% percent of us are eating enough fiber, and in effect, getting enough butyrate from our microbiomes. I think that contributes to some of these chronic diseases we’ve been seeing in high-income countries, and that are now on the rise in lower- and middle-income countries.”From Dammon’ s blog, How Can I Increase Butyrate Production?
This doesn’t mean rushing to your doctor and asking for a butyrate infusion or pill, he cautioned.
“People's knee jerk will be to consider giving butyrate therapeutically,” he said. “This has been done in metabolic disease, but with limited benefit.”
Other practitioners concur, including myself, that supplements are generally disappointing, although they have worked for some people.
Ready made butyrate in the from of tributyrate found in butter, but I have eaten lots of raw butter without noticing much benefit for the gut, but there are many other benefits from the cholesterol.
The main source of butyrate is by fermenting a variety of prebiotic fibers in the gut across formal categories of starches.
The challenge is to find what you can tolerate among many options, probably not the standard grains and beans, more like tubers, root vegetables and fruit and odd ball sources like cacoa.
There may be only one to start with if you take probiotics first or ferment the starch itself, which I don’t want to explain how to do here.
One of the reasons people don’t tolerate fibers is because they lack bacteria to digest or ferment them. Probiotics can come first. And it’s not just a matter taking directly ones the ferment probiotics, but using colonizing species to push back the pathogens that occupy by default, to make room for the others to grow.
Bifidobacterium, Faecalibacterium, Eubacterium, and Roseburia create butyrate. Some are in supplements some are not. It’s not necessary to take all directly.
You can’t just eat fermented foods randomly for difficult chronic conditions: you don’t know what you are getting and they probably won’t be enough.
Histamines problems are a probiotic imbalance that can be treated with probiotics.
Gut programs are very individualized. Each pro and prebiotics should be energetiically tested. It seems that is what is not good can throw you off so it is not effective to shot gun with many options and guess.
Here are some highlight starting with perhaps the most important first role in healing a leaky gut that overloads your body with toxins and drains and dysregulates the immune system.
When you seal up the leaky gut you can stop draining your whole body of energy and start to heal: detoxify, let the immune system to gain strength against pathogens, and get digestion working to extract energy from food. When the gut goes, everything goes.
Butyrate is the main source of fuel for colon cells so colonoyctes that are fed directly from the colon and not a blood supply.
When these are weak you get loose cell junctions or leaky gut.
What leaks through are toxins and endotoxins from pathogens like LPS, lipopolysaccharides.
You also get slow peristalsis or constipation.
Local inflammation and bloating follows as an attempt at healing a weak area.
Systemic inflammation can follow from a lack of butyrate in its larger hormonal type regulatory role in the immune system.
Some people find that histamines and mast cells respond to butyrate treatment. Jessica Kan (founder of BodyBio) says butyrate makes mast cell degranularize.
Butyrate also increases insulin sensitivity to burn carbs for energy rather that store as fat.
It also seems to have other roles in weight loss.
Butyrate is also important in Hormonal regulation
Increases testosterone.
Helps fertility, pcos, endometriosis, menstrual pain, etc.
Dr Stephen Gundry estimates we can get 10% of our energy from butyrate.
Butyrate experent Dr Chris Dammon says: “What is less appreciated is that butyrate, even at low levels, has direct effects on immune cells and neurons in the gut, body and brain,.”
“Butyrate could be the vitamin D of the next decade: the sunshine from within molecule.” Damman said. “Only 5% percent of us are eating enough fiber, and in effect, getting enough butyrate from our microbiomes. I think that contributes to some of these chronic diseases we’ve been seeing in high-income countries, and that are now on the rise in lower- and middle-income countries.”From Dammon’ s blog, How Can I Increase Butyrate Production?
This doesn’t mean rushing to your doctor and asking for a butyrate infusion or pill, he cautioned.
“People's knee jerk will be to consider giving butyrate therapeutically,” he said. “This has been done in metabolic disease, but with limited benefit.”
Other practitioners concur, including myself, that supplements are generally disappointing, although they have worked for some people.
Ready made butyrate in the from of tributyrate found in butter, but I have eaten lots of raw butter without noticing much benefit for the gut, but there are many other benefits from the cholesterol.
The main source of butyrate is by fermenting a variety of prebiotic fibers in the gut across formal categories of starches.
The challenge is to find what you can tolerate among many options, probably not the standard grains and beans, more like tubers, root vegetables and fruit and odd ball sources like cacoa.
There may be only one to start with if you take probiotics first or ferment the starch itself, which I don’t want to explain how to do here.
One of the reasons people don’t tolerate fibers is because they lack bacteria to digest or ferment them. Probiotics can come first. And it’s not just a matter taking directly ones the ferment probiotics, but using colonizing species to push back the pathogens that occupy by default, to make room for the others to grow.
Bifidobacterium, Faecalibacterium, Eubacterium, and Roseburia create butyrate. Some are in supplements some are not. It’s not necessary to take all directly.
You can’t just eat fermented foods randomly for difficult chronic conditions: you don’t know what you are getting and they probably won’t be enough.
Histamines problems are a probiotic imbalance that can be treated with probiotics.
Gut programs are very individualized. Each pro and prebiotics should be energetiically tested. It seems that is what is not good can throw you off so it is not effective to shot gun with many options and guess.
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