Testosterone in Women
Female androgen metabolism: Testosterone
In women, testosterone is produced in various locations. One quarter of the hormone is produced in the ovary, a quarter is produced in the adrenal gland, and one half is produced in the peripheral tissues from the various precursors produced in the ovaries and adrenal gland. There is also much interconversion among steroid hormones. The main precursor in the ovary is androstenedione, which is converted primarily to estrone, but which can also be converted to androgens. The main precursors in the adrenal gland are DHEA and DHEA-S. It is, therefore, reasonable to expect the symptoms of testosterone deficiency after menopause, since nearly
half of the testosterone is manufactured by the ovary, although the post-menopausal ovary still produces some steroid hormones.
www.bumc.bu.edu/sexualmedicine/publications/testosterone-insufficiency-in-women-fact-or-fiction/?fbclid=IwY2xjawIxi1NleHRuA2FlbQIxMQABHdYNRtb8k0PRNNbbyZnpK1mIWnt3lwOXQhwEuoMuS6DLFOIsu_K0w0OhuQ_aem_Atxt6I3JtF8ScxcAHAb1pQ
In women, testosterone is produced in various locations. One quarter of the hormone is produced in the ovary, a quarter is produced in the adrenal gland, and one half is produced in the peripheral tissues from the various precursors produced in the ovaries and adrenal gland. There is also much interconversion among steroid hormones. The main precursor in the ovary is androstenedione, which is converted primarily to estrone, but which can also be converted to androgens. The main precursors in the adrenal gland are DHEA and DHEA-S. It is, therefore, reasonable to expect the symptoms of testosterone deficiency after menopause, since nearly
half of the testosterone is manufactured by the ovary, although the post-menopausal ovary still produces some steroid hormones.
www.bumc.bu.edu/sexualmedicine/publications/testosterone-insufficiency-in-women-fact-or-fiction/?fbclid=IwY2xjawIxi1NleHRuA2FlbQIxMQABHdYNRtb8k0PRNNbbyZnpK1mIWnt3lwOXQhwEuoMuS6DLFOIsu_K0w0OhuQ_aem_Atxt6I3JtF8ScxcAHAb1pQ
